Bioinformatics Jobs

Jobs - Julie Bukar - Founder - JGB BioPharma Consulting Inc

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1) R & D Scientist (Senior Scientist) – Full Time (San Francisco or Greater Bay Area) W146KQ

2) Director of Technology Transfer – Full Time (San Francisco or Greater Bay Area) YP146B

3) Vice President, Research and Development – Full Time (New York) T143BR

4) (Senior) Bioinformatics Scientist – Full Time (New York) GP143V

5) Principal Genome Scientist – Full Time (San Francisco/Peninsula/Marin/Sonoma/Napa/Santa Rosa/Petaluma) AT103J

6) Senior Java Server Developer - Bioinformatics – Full Time (San Francisco/Peninsula/Marin/Sonoma/Napa/Santa Rosa/Petaluma) P103LA

7) Senior Front End Developer for Bioinformatics – Full Time (San Francisco/Peninsula/Marin/Sonoma/Napa/Santa Rosa/Petaluma) FB103T

8) Senior Manager, Bioinformatics – Full Time Position (Midwest) B73FN

9) Sr. Staff Scientist, Translational Medicine – Full Time (Midwest) M73QL

10) Staff Scientist, Bioinformatics – Full Time (Midwest) W73BH

11) Scientist III, Bioinformatics – Full Time Position (Midwest) P73NA


1) R & D Scientist (Senior Scientist) – Full Time (San Francisco or Greater Bay Area) W146KQ

DESCRIPTION:

  • The successful candidate will be a self-starter, enjoy working in a fast-paced multidisciplinary team environment, and be motivated to develop technologies with a significant clinical impact.
  • Leading in-lab efforts to develop novel nucleic acid based tests, including planning, feasibility testing, protocol development, optimization, verification and validation, and launch
  • Designing and coordinating the execution of effective experiments and analyzing data
  • Making experimental decisions to meet timelines
  • Documenting research progress under a quality management system
  • Communicating progress directly with colleagues and senior management

EXPERIENCE AND QUALIFICATIONS:

  • Track record of originating new methodologies and developing novel nucleic acid techniques.
  • Experience with nucleic acid technology relating to PCR, qPCR, multiplex PCR, and digital PCR.
  • Experience with next generation sequencing.
  • Demonstrated success in applying independent scientific judgment in experimental design and analysis.
  • Proven success in managing collaborative and individual projects, skills at writing clear SOPs and reports, and experience with Design Control a plus.
  • Strong analytical and problem solving skills.
  • Adept with Excel, basic statistical analysis.
  • Programming (e.g. PERL, python) and databases experience (SQL) a plus.
  • Strongly prefer Ph.D. in molecular biology or closely a related field and at least 4 years of industry experience.

To apply for a position send your resume to Jobs@JGBBioPharma.com

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2) Director of Technology Transfer – Full Time (San Francisco or Greater Bay Area) YP146B

DESCRIPTION:

  • Looking for a highly motivated person with excellent communication skills and a scientific background to manage relationships and partnerships with research and clinical partners 
  • Position will report to the Vice President of Research & Development
  • Work closely with R&D as well as business development to create and maintain a comprehensive plan for technology transfer, implementation, and support. 
  • Able to create and deliver technical presentations; create service and support plans; write laboratory manuals, IFUs, and workflow documents.
  • Demonstrate the highest level of professionalism while managing and maintaining partner relationships.
  • Deliver the highest level of responsiveness for partner communications, logistics, training, trouble-shooting, and ongoing technical support.
  • Ability and desire to work within a quality system that is compliant with FDA and European medical device regulations.

EXPERIENCE AND QUALIFICATIONS:

  • Proven effectiveness in communicating with individuals across various corporate functions including sales, business development, and research and development.
  • Able to travel 5-10% of the time.
  • Demonstrable success in developing and implementing plans and managing projects
  • Experience with development activities such as trouble-shooting, optimization, verification, and validation.
  • Knowledge of various regulations such as CLIA, CAP, 21CFR 820, 806, 803, 210, 211, European In-Vitro Diagnostic Directive 98/79/EC, EN ISO 13485:2012 preferred.
  • Knowledge of DNA sequencing, qPCR, PCR, and related methods preferred.
  • PhD or MS in molecular biology or related field and at least 4 years of hands on experience in molecular diagnostic assay research, development, and deployment.

To apply for a position send your resume to Jobs@JGBBioPharma.com

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3) Vice President, Research and Development – Full Time (New York) T143BR

DESCRIPTION:

  • Work closely with the senior leadership team to set short, medium, and long-­term goals for the research team in the context of larger business milestones
  • Managing the day-­to-­day activities of a diverse team of biologists, bioinformaticians, and data scientists to ensure that goals are met
  • Prioritize and translate research discoveries in a clinical and business context
  • Help develop a culture of leadership, mentorship, and collaboration
  • Take the lead in developing presentations and publication ready papers
  • Developing  and managing  a  budget
  • Participate in fundraising efforts (government grants, private capital)

EXPERIENCE AND QUALIFICATIONS:

  • Managing collaborative and interdisciplinary research projects
  • Managing, coaching, mentoring and motivating employees for exceptional performance
  • Managing operations in an industry setting or senior academic post (core facility leadership/laboratory head)
  • Communicating research findings through lectures and publications
  • Developing a budget and participating in fundraising efforts (government grants, private capital)
  • Proficiency in the fundamentals of genetics, genomics, statistical analysis, and data science
  • Strong organizational, written, and communication skills
  • Good analytical and problem solving abilities
  • A proven publication record
  • Experience in genetic biomarker discovery research
  • Experience in reproductive biology or early development is highly preferred
  • Enjoys working in a highly collaborative environment with a diverse team to tackle complex problems
  • Is disciplined and driven to deliver ongoing research results
  • Has a positive attitude with a willingness to roll up their sleeves and do what it takes to get the job done
  • Highly organized
  • Strong written and verbal communicator
  • MD or PhD in the Biological Sciences or a related field

To apply for a position send your resume to Jobs@JGBBioPharma.com

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4) (Senior) Bioinformatics Scientist – Full Time (New York) GP143V

DESCRIPTION:

  • Working with standard bioinformatics tools and visualization packages
  • Automating and refining the processing and analysis of large data sets
  • Developing and using bioinformatics pipelines to prepare and analyze data
  • Designing, developing, and maintaining databases for scientific and commercial applications
  • Analyzing and working with NGS data, ideally whole genome sequence data


EXPERIENCE AND QUALIFICATIONS:

  • PhD in Bioinformatics, Computational Biology, Computer Science, Mathematics, Statistics, Genetics, Biology or related Genetics field with additional postdoctoral or industry experience (for Senior role)    
  • Proficiency in Python, Perl, Java, C/C++, and R programming
  • Good working knowledge of current best practices in genetic variant discovery, variant analysis, and validation methods
  • Experience with Whole Genome sequence data required (e.g. not microbes, plants etc.)
  • Strong organizational, written, and communication skills
  • Good analytical and problem solving abilities
  • A proven publication record
  • Experience in human genetics is highly preferred
  • Enjoys working in highly collaborative environment with diverse team to tackle complex problems
  • Is disciplined and driven to deliver ongoing research results
  • Has a positive attitude with willingness to be hands on when needed
  • Highly organized
  • strong written and verbal communicator
  • Has hard work ethic with emphasis on execution

To apply for a position send your resume to Jobs@JGBBioPharma.com

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5) Principal Genome Scientist – Full Time (San Francisco/Peninsula/Marin/Sonoma/Napa/Santa Rosa/Petaluma) AT103J

DESCRIPTION:

  • Provides scientific and technical leadership for the development of the product for rapid identification of disease-causing variants from genome and exome sequencing datasets.  
  • This position also interacts with the community, customers, and key opinion leaders to drive scientific collaborations, grant proposals, and scientific service deliverables that advance the capabilities, customer value and awareness for genome informatics solutions.  
  • The Principal Genome Scientist routinely represents the company as a scientific lead at industry conferences and key customer meetings and events.

EXPERIENCE AND QUALIFICATIONS:

  • Extensive knowledge and background with analysis and interpretation of next generation sequencing data, with direct experience identifying variants driving human disease and/or therapeutic response.  
  • Experience working closely with a software development team is a strong plus.
  • Team player, excellent communicator

To apply for a position send your resume to Jobs@JGBBioPharma.com

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6) Senior Java Server Developer - Bioinformatics – Full Time (San Francisco/Peninsula/Marin/Sonoma/Napa/Santa Rosa/Petaluma) P103LA

DESCRIPTION:


  • Looking for an experienced server-side developer who has a good eye for software architecture and API design, and a proven track record of building scalable bioinformatics / scientific software systems for big data analysis workflows in genomics and life sciences. 
  • This position will help build out the industry-leading genomic data analysis cloud platform for large scale scientific and clinical data analysis and management. 
  • Experience with genomics, bioinformatics and life sciences is required.
  • As a senior back end developer, you will develop software and infrastructure used to deliver the  cloud-based product line to a global community of researchers, scientists, clinicians and medical geneticists. 
  • Work closely with our scientific product leads, bioinformaticians, and front end developers on developing big data management frameworks, tooling, applications and reporting / visualizations that support large-scale, sophisticated data analysis and interpretation of genomic and genetic data. The solutions you develop will be used by molecular biologists, clinical geneticists and researchers, and biomedical informaticians, and will fundamentally enable the application of technologies for the improvement of human health.
  • A good fit would be a rock star Java developer with an aptitude for tackling complex data processing, analysis and workflow challenges in the life sciences. You will need a strong analytical mindset and a talent for executing quickly while still following best practices and who thrives on new technology and has an avid interest in bioinformatics and genomics. Use a hybrid web stack, with mostly Java on the back end but some Python and Perl as well. You will be expected to help make decisions on server-side library and framework usage, including both generic software frameworks as well as ones focused on life sciences and bioinformatics, as well as scaling our distributed computing cloud configuration supporting large scale data management and processing for our customers around the world.

EXPERIENCE AND QUALIFICATIONS:

  • Bachelor’s or Master’s Degree in Bioinformatics, Computational Science, Biological Life Science
  • 5+ years of recent Java development experience – this is a primary requirement.
  • 5+ years’ working experience involving Bioinformatics software bioinformatics tools and biological databases
  • 3+ years’ experience building NGS pipelines for processing human sequencing data from at least Illumina and Ion Torrent platforms
  • 3+ years working in a team-based agile development environment
  • Familiarity with Linux required, experience with Python and Bash scripting preferred
  • Understanding of Next Generation Sequencing technique and expertise with NGS bioinformatics tools such as GATK, Bowtie, etc
  • PhD in Bioinformatics or Computational Science preferred
  • 8+ years bioinformatics development experience in a research or translational setting
  • Experience working with both DNA-Seq and RNA-Seq data
  • Experience with commercial and open source NGS pipeline infrastructure tooling and cloud infrastructure like Amazon Web Services, Heroku, etc
  • Strong experience with Python language and libraries; 3+ years applying Python scripting to bioinformatics preferred
  • Strong communication skills and willingness to ask a question. We do not typically assign 100% specced-out tasks that always must be implemented an exact way; you'll be given a business problem to solve for the user, and expected to understand and explore the space of design alternatives to come up with a good solution, using rapid prototyping to test your design hypotheses. Questions will occur and it is important that you be comfortable asking them and chasing down answers.
  • Know how to optimizing complex distributed software systems in a cloud deployed environment.
  • Strong believer in version control tooling and know your way around git and Github.
  • Resourceful and can pull down a Java or Python project and get running on development the same day.
  • Like working with teams on large apps where modularity, performance, flexibility, maintainability, and API integration are fundamental concepts that inform your code and architecture decisions.

To apply for a position send your resume to Jobs@JGBBioPharma.com

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7) Senior Front End Developer for Bioinformatics – Full Time (San Francisco/Peninsula/Marin/Sonoma/Napa/Santa Rosa/Petaluma) FB103T

DESCRIPTION:

  • Will lead front end development on the DataStream tools used to deliver the entire company product line to the customers, and to integrate products and platform technology into a wide range of scientific workflows across academia, pharma, biotech and clinical settings. 
  • Will work closely with the scientific product leads, bioinformaticians, and back end developers on developing tools and visualizations that support large-scale, sophisticated data analysis and interpretation. 
  • The solutions you develop will be used by molecular biologists, clinical geneticists and researchers, and biomedical informaticians, and will fundamentally enable the application of company technologies for the improvement of human health.
  • A good fit would be a developer who can execute quickly while still following best practices and who thrives on new technology and has an avid interest in bioinformatics and genomics. Using a hybrid web stack, with mostly Java on the back end but some Python and Perl as well. 
  • Expected to help make decisions on front-end library usage, front-end and javascript architecture, and lead implementation of CSS, HTML and JS. Help evaluate and select modern tooling (such as SASS, Coffeescript, Grunt) and selectively apply techniques in the space (such as Raphael, D3, Backbone). 
  • Talented front-end developer who writes clean, well-organized CSS and HTML and composes Javascript beyond the walled garden of JQuery.

EXPERIENCE AND QUALIFICATIONS:

  • A bioinformatics degree is not required for this position, but experience building web-based user interfaces or information visualizations for biomedical researchers, scientists and clinicians is a must.
  • Exceptional HTML5, CSS and JavaScript skills, JKQuery
  • Experience working with Java backends a must; Java software development experience strongly preferred.
  • MVC, SVN, Linux command line
  • Demonstrated ability to quickly and independently implement MVC sites using Bootstrap or similar frameworks.
  • Strong attention to detail and visual design -- please expect to show your portfolio
  • Bonus: experience with CoffeeScript, SASS, Django and similar
  • Bonus: experience with JS app and visualization frameworks: EmberJS, Angular, Backbone, D3
  • Strong experience with MVC client-side libraries, having done one or more substantial projects with a framework such as Backbone or Ember.
  • Experience : built web applications that involve multiple user roles working together in a multi-step workflow
  • Have demonstrated design skills for rich data-driven web apps
  • Projects to identify what’s missing or unworkable in a wireframe or high-level set of design requirements, and have the basic design and UX chops to improvise when necessary.
  • Strong communication skills and willingness to ask a question. 
  • Expected to understand and explore the space of design alternatives to come up with a good solution, using rapid prototyping to test your design hypotheses. 
  • Know how to optimizing website resources and front-end performance for data-heavy Javascript apps
  • Should be comfortable and effective using SASS (or LESS, Stylus, etc.) and know your way around Grunt, Bower, etc. Coffeescript tolerance is a plus.
  • Well-versed in the classic front end skills as well - you know your meta tags, SEO basics, and analytics / user tracking, and can deal with IE8 etc. should the unfortunate necessity arise.
  • Version control tooling and know your way around git and Github.
  • Resourceful and can pull down a PHP or Ruby project and get running on development the same day.
  • Like working with teams on large apps where performance, responsive design and API integration are fundamental concepts that inform your code and architecture decisions.

To apply for a position send your resume to Jobs@JGBBioPharma.com

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8) Senior Manager, Bioinformatics – Full Time Position (Midwest) B73FN

DESCRIPTION:

The purpose of this position is to lead a bioinformatics team that focuses on two areas:  (1) develop and maintain the informatics pipelines and algorithms that comprise our knowledge base, and (2) provide project-based bioinformatics support to the Pharma and Clinical Diagnostic Services business to enable the application of cancer knowledge base and bioinformatics methods.
This team mission is to develop and continuously improve methods for identifying the driver aberrations in cancer through the systematic analysis of high-throughput molecular profiling data.

RESPONSIBILITIES

  • Manage a bioinformatics team that provides: Algorithm and method development in support of the continuous growth and improvement of core compendium of genomic data and cancer knowledge. and Project based bioinformatics support to our Pharma Services and Clinical Diagnostics businesses
  • Organizing and leading the Bioinformatics team to ensure a robust and scalable end to end working bioinformatics pipeline and, working with customers and other teams, provide custom bioinformatics analysis and solutions.
  • Provide strategic direction and guidance to Bioinformaticians in their daily analysis and product development efforts as well as their individual career development and growth.
  • Critical assessment of experimental data to identify patterns that improve content usability to answer core questions
  • Guide team in matrixed environment. Ability to allocate development resources to staff projects appropriately in that environment.
  • Provide accurate scoping and estimation of development efforts for projects based on product requirements and a solid grasp of the relevant bioinformatics tools.
  • Investigate, create and develop new methods and technologies for project advancement.
  • Coordination with other R&D functions as well as Product Management and Marketing to identify critical product development features to prioritize for future releases
  • Communication and coordination with leadership to promote effective systems development.
  • Maintain high level of professional expertise through familiarity with current scientific literature, competing technologies and/or products and attendance of scientific seminars and meetings.
  • Communicates the significance of recent scientific and technology developments to peer group.
  • Collaborate with sequencing teams and clinical researchers to qualify product performance.
  • When needed, select external vendors and consultants and manage engagements.
  • Enthusiasm to collaborate with other departments as a technical consultant.
  • Serve as internal technical expert

EXPERIENCE AND QUALIFICATIONS:

  • Expertise in both bioinformatics and genomics applications is required.
  • Proven understanding and experience in the fields of genomics, experimental data processing, high-throughput data analysis, and genomic databases. 
  • Understanding of basic biology and cancer biology a must.
  • Firm grasp of univariate statistical analysis fundamentals necessary. 
  • Experience with multivariate statistics or statistical modeling a plus.
  • Candidates should have knowledge of leading NGS processing techniques for the quantification of gene expression and copy number, and the identification of somatic mutations, gene fusions, and genomic rearrangements.  Direct experience processing NGS data is a plus.  Candidates should be familiar with the limitations of the various NGS platforms and informatic pipelines, so that data are appropriately integrated into analyses.
  • Strong computational skills, particularly in data parsing, cleansing, data modeling, analysis, and database design and implementation.
  • Solid knowledge of unix/linux. Experience with cluster computing a plus.
  • Previous bioinformatics and scientific programming experience necessary; experience with Spotfire, Pipeline Pilot, R, SQL, and NGS a plus.
  • Ability to review, synthesize, and present scientific data and methods.
  • Good written and verbal communication skills.
  • Inspires, motivates and collaborates with others.
  • Anticipates needs and problems while creating solutions.
  • 7 or more years of post-graduate work experience
  • PhD in computer science, computational biology, biostatistics, bioinformatics, or similar (MS acceptable for the candidate with the right experience)

To apply for a position send your resume to Jobs@JGBBioPharma.com

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9) Sr. Staff Scientist, Translational Medicine – Full Time (Midwest) M73QL

DESCRIPTION:

  • Provide leadership in the application of cancer data sciences to translational medicine and diagnostics opportunities. 
  • Will be expected to exhibit scientific leadership of cancer genome data sciences.
  • Provide scientific review, and ensure that results intended for internal and external customers are presented clearly and effectively.
  • Strong scientific and technical leadership is expected, along with ability to foster collaboration and innovation from the Translational Medicine team.
  • Partner with bioinformatics colleagues to develop and assess bioinformatics strategies.
  • Contribute to the development of innovative methods, software platforms, and infrastructure.
  • Support and/or lead the development of scientific presentations for scientific conferences and publications.
  • May be required to perform other related duties as required and/or assigned. 

EXPERIENCE AND QUALIFICATIONS:

  • Requires a minimum of  5 years of relevant post-graduate experience in a cancer focused translational medicine related field. Industry experience is a plus.
  • Requires demonstrated expertise and experience working with cancer genomics data, along with a solid understanding of tumor biology and oncogenic signaling pathways.
  • Proven scientific excellence exemplified by lead author publications in high impact trade journals and/or significant contributions to industry programs.
  • Ability to work independently and collaboratively.
  • Requires ability to communicate effectively in spoken and written English language.
  • Prior work experience in industry or tenure-track academic position preferred.
  • Solid understanding of common statistical approaches used with genomic data preferred. 
  • PhD and/or MD in relevant field required.

To apply for a position send your resume to Jobs@JGBBioPharma.com

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10) Staff Scientist, Bioinformatics – Full Time (Midwest) W73BH

DESCRIPTION:

  • Seeking individuals with expertise in bioinformatics and an understanding of the cancer genome to identify cancer driver aberrations and to associate those genetic events with potential therapeutic strategies.  
  • Work collaboratively in a matrix environment to develop data analysis strategies to address key questions about cancer for our internal and external customers.  
  • Applications include diagnostics, target and biomarker discovery, indication selection, and clinical development strategies.
  • Collaborate with Medical Sciences Informatics (MSI) colleagues to understand our customer’s questions about cancer, patients, and drugs, and develop data analysis strategies and plans to answer them.
  • Implement bioinformatics data integration and analysis pipelines in Pipeline Pilot and/or scripting languages, drawing on MSI's large collection of high-throughput genomic data and sample annotations.
  • Develop visualization environments in Spotfire to enable scientists to explore the data and answer questions.
  • Written and verbal presentation of results and methods.
  • May be required to perform other related duties as required and/or assigned.

EXPERIENCE AND QUALIFICATIONS:

  • Proven understanding and experience in the fields of genomics, experimental data processing, high-throughput data analysis, and genomic databases. Understanding of basic biology and cancer biology a must.
  • Firm grasp of univariate statistical analysis fundamentals necessary. Experience with multivariate statistics or statistical modeling a plus.
  • Candidates should have knowledge of leading NGS processing techniques for the quantification of gene expression and copy number, and the identification of somatic mutations, gene fusions, and genomic rearrangements.  Direct experience processing NGS data is a plus.  Candidates should be familiar with the limitations of the various NGS platforms and informatic pipelines, so that data are appropriately integrated into analyses.
  • Strong computational skills, particularly in data parsing, cleansing, data modeling, analysis, and database design and implementation.
  • Solid knowledge of unix/linux. Experience with cluster computing a plus.
  • Previous bioinformatics and scientific programming experience necessary; experience with Spotfire, Pipeline Pilot, R, SQL, and NGS a plus.
  • Ability to review, synthesize, and present scientific data and methods.
  • Good written and verbal communication skills.
  • Inspires, motivates and collaborates with others.
  • Anticipates needs and problems while creating solutions.
  • 5 years of post-graduate work experience
  • PhD in computer science, computational biology, biostatistics, bioinformatics, or similar (MS acceptable for the candidate with the right experience)

To apply for a position send your resume to Jobs@JGBBioPharma.com

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11) Scientist III, Bioinformatics – Full Time Position (Midwest) P73NA

DESCRIPTION:

  • Collaborate with scientists to understand customer’s questions about cancer, patients, and drugs, and to develop data analysis strategies and plans to answer them.
  • Collaborate with colleagues to understand our customer’s questions about cancer, patients, and drugs, and develop data analysis strategies and plans to answer them. 
  • Implement bioinformatics data integration and analysis pipelines in Pipeline Pilot and/or scripting languages, drawing on large collection of high-throughput genomic data and sample annotations. 
  • Develop visualization environments in Spotfire to enable scientists to explore the data and answer questions. 
  • Written and verbal presentation of results and methods. 
  • May be required to perform other related duties as required and/or assigned. 

EXPERIENCE AND QUALIFICATIONS:

  • Proven understanding and experience in the fields of genomics, experimental data processing, high-throughput data analysis, and genomic databases. 
  • Understanding of basic biology and cancer biology a must.
  • Firm grasp of univariate statistical analysis fundamentals necessary.  
  • Experience with multivariate statistics or statistical modeling a plus.
  • Strong computational skills, particularly in data parsing, cleansing, data modeling, analysis, and database design and implementation. 
  • Solid knowledge of unix/linux.  
  • Experience with cluster computing a plus. 
  • Ability to review, synthesize, and present scientific data and methods. 
  • Outstanding written and verbal communication skills. 
  • Previous bioinformatics and scientific programming experience necessary; experience with Spotfire, Pipeline Pilot, R, SQL, and NGS a plus. 
  • Scientific experience in cancer study and/or research a plus. 
  • Pharmaceutical experience and lead author publications are highly valued. 
  • Inspires, motivates and collaborates with others. 
  • Anticipates needs and problems while creating solutions.
  • Requires a Masters and/or PhD along with minimum 5 years post-graduate work experience in related field

To apply for a position send your resume to Jobs@JGBBioPharma.com

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